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For comparative purposes, a group treated with a similar dose of a GLP1 analog and a non-androgenized control group treated with a vehicle were also included

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This complex cleaves pro-IL-1 via caspase-1 to generate active IL-1 (a key inflammatory mediator), concurrently inducing gasdermin D-mediated pyroptosis

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doi: 10.1016/j.mce.2019.01.020 59 WangNSiCXiaLWuXZhaoSXuHet al

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